Abstract
Regional cerebral blood flow was measured with single photon emission computed tomography in 10 obsessive-compulsive patients and eight comparison subjects. The patients had a significantly higher ratio of medial-frontal to whole cortex blood flow; this was unrelated to symptom severity but was correlated negatively with anxiety. No differences in orbital-frontal blood flow were found.
Publication types
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Comparative Study
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adolescent
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Adult
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Anxiety / physiopathology
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Cerebral Cortex / blood supply
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Cerebral Cortex / physiopathology
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Cerebrovascular Circulation*
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Female
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Frontal Lobe / blood supply*
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Frontal Lobe / physiopathology
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Humans
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Male
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Middle Aged
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Obsessive-Compulsive Disorder / physiopathology*
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Organotechnetium Compounds
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Oximes
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Technetium Tc 99m Exametazime
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Tomography, Emission-Computed, Single-Photon*
Substances
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Organotechnetium Compounds
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Oximes
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Technetium Tc 99m Exametazime