17p13/TP53 deletion in B-CLL patients is associated with microRNA-34a downregulation

Leukemia. 2009 Mar;23(3):625-7. doi: 10.1038/leu.2008.264. Epub 2008 Sep 25.
No abstract available

Publication types

  • Letter

MeSH terms

  • Aged
  • Aged, 80 and over
  • Chromosome Deletion*
  • Chromosomes, Human, Pair 17 / genetics*
  • Down-Regulation
  • Exons / genetics
  • Female
  • Gene Expression Regulation, Leukemic
  • Genes, p53
  • Humans
  • Leukemia, Lymphocytic, Chronic, B-Cell / genetics*
  • Male
  • MicroRNAs / genetics*
  • Middle Aged
  • Sequence Analysis, DNA
  • Tumor Suppressor Protein p53 / deficiency

Substances

  • MIRN34 microRNA, human
  • MicroRNAs
  • Tumor Suppressor Protein p53