Developmental neuroscience: Hox and Fox

Nature. 2008 Sep 18;455(7211):295-7. doi: 10.1038/455295a.

Abstract

A network of Hox factors specifies the identity of motor neurons in the spinal cord. Studies of an essential Fox-class accessory factor illuminate the developmental and evolutionary subtlety of the process.

Publication types

  • News

MeSH terms

  • Animals
  • Biological Evolution
  • Cell Differentiation
  • Forkhead Transcription Factors / chemistry
  • Forkhead Transcription Factors / genetics
  • Forkhead Transcription Factors / metabolism*
  • Homeodomain Proteins / metabolism*
  • Mice
  • Motor Neurons / cytology
  • Motor Neurons / metabolism*
  • Repressor Proteins / chemistry
  • Repressor Proteins / genetics
  • Repressor Proteins / metabolism
  • Spinal Cord / cytology*
  • Spinal Cord / embryology*

Substances

  • Forkhead Transcription Factors
  • Foxp1 protein, mouse
  • Homeodomain Proteins
  • Repressor Proteins