Long-term (7-year-) treatment with lamivudine monotherapy in HBV-associated glomerulonephritis

Clin Nephrol. 2008 Jul;70(1):69-71. doi: 10.5414/cnp70069.

Abstract

Glomerulonephritis (GN) is an uncommon but well-described complication of chronic hepatitis B virus (HBV) infection. HBV-related membranous nephropathy (MN) may lead to renal failure in 1/3 of the patients and spontaneous remission is rare. There is no standard therapy for HBV-associated MN. We report a case of a 28-year-old man with HBV-associated MN due to pre-core HBV mutant with complete remission under an ongoing 7-year lamivudine monotherapy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Drug Administration Schedule
  • Glomerulonephritis / diagnosis
  • Glomerulonephritis / drug therapy*
  • Glomerulonephritis / virology*
  • Hepatitis B, Chronic / complications
  • Hepatitis B, Chronic / diagnosis
  • Hepatitis B, Chronic / drug therapy*
  • Humans
  • Lamivudine / administration & dosage*
  • Male
  • Reverse Transcriptase Inhibitors / administration & dosage*

Substances

  • Reverse Transcriptase Inhibitors
  • Lamivudine