Issues in the design and interpretation of chronic toxicity and carcinogenicity studies in rodents: approaches to dose selection

Crit Rev Toxicol. 2008;38(10):895-6; author reply 897-8. doi: 10.1080/10408440802116504.
No abstract available

Publication types

  • Comment
  • Letter

MeSH terms

  • Animals
  • Carcinogenicity Tests / methods*
  • Carcinogens / toxicity*
  • Dose-Response Relationship, Drug
  • Drug-Related Side Effects and Adverse Reactions*
  • Organ Size
  • Pathology, Clinical
  • Risk Assessment
  • Rodentia
  • Toxicity Tests, Chronic / methods*

Substances

  • Carcinogens