Biofilms and chronic wound inflammation

J Wound Care. 2008 Aug;17(8):333-41. doi: 10.12968/jowc.2008.17.8.30796.

Abstract

In contrast to the commonly accepted hypothesis of host-centred pathology, it is possible that surface bacteria, not host dysfunction, cause the chronicity and perpetual inflammation associated with chronic non-healing wounds.

Publication types

  • Review

MeSH terms

  • Biofilms*
  • Chronic Disease
  • Cytokines / metabolism
  • Host-Pathogen Interactions / immunology
  • Humans
  • Inflammation / immunology
  • Inflammation / microbiology*
  • Neutrophil Activation / immunology
  • Peptide Hydrolases / metabolism
  • Skin Ulcer / immunology
  • Skin Ulcer / microbiology*
  • Wounds and Injuries / immunology
  • Wounds and Injuries / microbiology*

Substances

  • Cytokines
  • Peptide Hydrolases