Hypothalamic papillary tumor in a patient with tuberous sclerosis

Am J Surg Pathol. 2008 Oct;32(10):1578-80. doi: 10.1097/PAS.0b013e318172621a.

Abstract

We here report an unusual tumor of the suprasellar region featuring a papillary growth pattern and cytokeratin expression in a 10-year-old boy with tuberous sclerosis. This hitherto undescribed low-grade hypothalamic tumor extends the spectrum of tumors associated with the tuberous sclerosis complex.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomarkers, Tumor / analysis
  • Child
  • DNA Mutational Analysis
  • Gene Expression Regulation, Neoplastic
  • Humans
  • Hypothalamic Neoplasms / chemistry
  • Hypothalamic Neoplasms / etiology
  • Hypothalamic Neoplasms / genetics
  • Hypothalamic Neoplasms / pathology*
  • Hypothalamic Neoplasms / therapy
  • Hypothalamus / chemistry
  • Hypothalamus / pathology*
  • Magnetic Resonance Imaging
  • Male
  • Treatment Outcome
  • Tuberous Sclerosis / complications*
  • Tuberous Sclerosis / pathology

Substances

  • Biomarkers, Tumor