Novelty seeking modulates medial prefrontal activity during the anticipation of emotional stimuli

Felix Bermpohl; Alvaro Pascual-Leone; Amir Amedi; Lotfi B Merabet; Felipe Fregni; Jana Wrase; Florian Schlagenhauf; Michael Bauer; Andreas Heinz; Gottfried Schlaug; Georg Northoff

doi:10.1016/j.pscychresns.2007.12.019

Novelty seeking modulates medial prefrontal activity during the anticipation of emotional stimuli

Psychiatry Res. 2008 Oct 30;164(1):81-5. doi: 10.1016/j.pscychresns.2007.12.019. Epub 2008 Aug 13.

Authors

Felix Bermpohl¹, Alvaro Pascual-Leone, Amir Amedi, Lotfi B Merabet, Felipe Fregni, Jana Wrase, Florian Schlagenhauf, Michael Bauer, Andreas Heinz, Gottfried Schlaug, Georg Northoff

Affiliation

¹ Berenson-Allen Center for Non-Invasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. felix.bermpohl@charite.de

PMID: 18703319
DOI: 10.1016/j.pscychresns.2007.12.019

Abstract

In a functional magnetic resonance imaging experiment, expectancy cues signaling emotional stimuli were used to study the personality trait of novelty seeking. BOLD responses to emotional expectancy were positively correlated with novelty-seeking scores in the medial prefrontal cortex. This correlation was strongest for the sub-dimension of exploratory excitability.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Affect / physiology*
Exploratory Behavior*
Humans
Magnetic Resonance Imaging
Prefrontal Cortex / physiology*
Temperament