Does black blood MRA have a role in the assessment of intracerebral aneurysms?

Eur Radiol. 2009 Jan;19(1):184-92. doi: 10.1007/s00330-008-1127-2. Epub 2008 Aug 9.

Abstract

The aim of this study was to assess whether the addition of a black blood (BB) sequence to standard three-dimensional time-of-flight (3D-TOF) imaging yields improved quantitative assessment of intracranial aneurysms. Thirty seven patients with 42 proven intracranial aneurysms underwent intra-arterial digital subtraction angiography, 3D-TOF and BB MRI imaging. This multimodality imaging was used to create a composite reference aneurysm description. The 3D-TOF and BB imaging were graded on a subjective seven-point scale to determine what improvement if any the addition of BB imaging yielded. Comparison of measurements from all imaging modalities demonstrated no significant difference (p < 0.01) in aneurysm length/width or parent vessel width. Aneurysm neck measurements were underestimated on 3D-TOF images although there was still a significant correlation (R(2) = 0.72, p < 0.05). Comparison of TOF and BB examinations to the composite reference using the Wilcoxon signed-rank test showed significant improvement in the demonstration of the aneurysm to parent/branch vessels and the morphology/size of the aneurysm neck, particularly in the setting of local haematoma or slow flow (p < 0.001). We propose the addition of the BB sequence as a useful adjunct to 3D-TOF imaging particularly when detailed aneurysm morphology is required or there is thrombus in subarachnoid space.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Aged
  • Algorithms*
  • Female
  • Humans
  • Image Enhancement / methods
  • Image Interpretation, Computer-Assisted / methods*
  • Imaging, Three-Dimensional / methods*
  • Intracranial Aneurysm / diagnosis*
  • Magnetic Resonance Angiography / methods*
  • Male
  • Middle Aged
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Young Adult