2,3-Heteroaromatic ring-fused cyclohexanones via heteroaromatic homo-Nazarov cyclization of donor-acceptor substituted cyclopropanes

Chem Commun (Camb). 2008 Aug 28:(32):3774-6. doi: 10.1039/b805348k. Epub 2008 Jun 18.

Abstract

Heteroaryl 2-silylmethyl-substituted cyclopropyl ketones rearrange under Lewis acid conditions via heteroaromatic homo-Nazarov cyclization to form 2,3-heteroaromatic ring fused 4-t-butyldiphenylsilylmethyl-substituted cyclohexanones.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cyclization
  • Cyclohexanones / chemical synthesis*
  • Cyclopropanes / chemistry*
  • Heterocyclic Compounds / chemical synthesis*
  • Indicators and Reagents
  • Trimethylsilyl Compounds / chemistry

Substances

  • Cyclohexanones
  • Cyclopropanes
  • Heterocyclic Compounds
  • Indicators and Reagents
  • Trimethylsilyl Compounds
  • cyclopropane