Abstract
A prospective, school-based study included daily monitoring for incidence of symptomatic streptococcal-associated pharyngitis and monthly determinations of group A streptococcal prevalence. A treatment group received penicillin/erythromycin therapy at school for positive throat cultures; the control group sought medical care from their regular provider. Prevalence and incidence of group A streptococcal pharyngitis were significantly lower among the treatment group than in the controls.
Publication types
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Controlled Clinical Trial
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / administration & dosage
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Anti-Bacterial Agents / therapeutic use*
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Carrier State / drug therapy
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Carrier State / epidemiology
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Carrier State / microbiology
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Carrier State / prevention & control
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Child
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China / epidemiology
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Delivery of Health Care / methods
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Erythromycin / administration & dosage
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Erythromycin / therapeutic use
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Female
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Humans
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Incidence
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Male
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Penicillins / administration & dosage
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Penicillins / therapeutic use
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Pharyngitis / drug therapy
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Pharyngitis / epidemiology
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Pharyngitis / microbiology
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Pharyngitis / prevention & control*
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Pharynx / microbiology
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Prevalence
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Program Evaluation*
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Respiratory Tract Infections / drug therapy
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Respiratory Tract Infections / epidemiology
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Respiratory Tract Infections / microbiology
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Respiratory Tract Infections / prevention & control
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Schools* / statistics & numerical data
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Streptococcal Infections / drug therapy
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Streptococcal Infections / epidemiology
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Streptococcal Infections / microbiology
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Streptococcal Infections / prevention & control*
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Streptococcus pyogenes / drug effects*
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Streptococcus pyogenes / isolation & purification
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Treatment Outcome
Substances
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Anti-Bacterial Agents
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Penicillins
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Erythromycin