Abstract
Adalimumab, an anti-tumour necrosis factor agent, especially used in the treatment of rheumatoid arthritis, has a good safety profile. One of the most common side-effects of adalimumab is the development of autoantibodies. Despite the induction of autoantibodies, the clinical presentation of immune-mediated complications upon adalimumab therapy, including a lupus-like syndrome, is very rare. We have recently evaluated a new case of adalimumab-induced lupus erythematosus.
MeSH terms
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Adalimumab
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Antibodies, Monoclonal / adverse effects*
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Antibodies, Monoclonal, Humanized
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Antirheumatic Agents / adverse effects*
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Arthritis, Rheumatoid / drug therapy*
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Arthritis, Rheumatoid / immunology
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Autoantibodies / immunology
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Female
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Humans
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Lupus Erythematosus, Systemic / chemically induced*
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Lupus Erythematosus, Systemic / immunology
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Lupus Erythematosus, Systemic / pathology
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Middle Aged
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Skin / pathology
Substances
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Antibodies, Monoclonal
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Antibodies, Monoclonal, Humanized
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Antirheumatic Agents
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Autoantibodies
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Adalimumab