Vestibular neuritis: vertigo and the high-acceleration vestibulo-ocular reflex

J Neurol. 2008 Oct;255(10):1479-82. doi: 10.1007/s00415-008-0935-2. Epub 2008 Jul 11.

Abstract

Patients after vestibular neuritis (VN) often report persistent dizziness and disequilibrium. We correlated persistent symptoms with sustained impairment of the high-acceleration horizontal vestibulo-ocular reflex as determined by quantitative searchcoil head-impulse testing (qHIT). In 47 patients, qHIT was recorded 0-60 months and symptoms assessed with the Yardley Vertigo Symptom Scale short form > or = 18 months after VN onset. No correlation between the magnitude of high-acceleration vestibular impairment and the severity of vertigo symptoms was observed. The lack of a symptom-qHIT correlation suggests that defective compensation at a more rostral level in the central nervous system may be responsible for protracted symptoms in VN patients.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Dizziness / physiopathology
  • Eye Movements
  • Female
  • Head Movements
  • Humans
  • Male
  • Middle Aged
  • Reflex, Vestibulo-Ocular / physiology*
  • Vertigo / physiopathology*
  • Vestibular Neuronitis / physiopathology*