Evaluation and management of the adult patient with transposition of the great arteries following atrial-level (Senning or Mustard) repair

Nat Clin Pract Cardiovasc Med. 2008 Aug;5(8):454-67. doi: 10.1038/ncpcardio1252. Epub 2008 Jul 1.

Abstract

Atrial-level repair for transposition of the great arteries is one of the greatest achievements of modern cardiovascular medicine, transforming a once fatal congenital heart condition into one with excellent long-term survival. Although atrial-level repair has been supplanted by the arterial switch, there remains a population of patients who underwent atrial-level repair as children and now require ongoing care as adults. Survival slowly continues to decline in this population mainly owing to systemic right ventricular dysfunction and sudden death. Other problems include sinus node dysfunction, atrial arrhythmias, systemic atrioventricular valve regurgitation, baffle problems, and pulmonary hypertension. Evaluation and management of these late complications is addressed.

Publication types

  • Review

MeSH terms

  • Adult
  • Cardiovascular Surgical Procedures / adverse effects
  • Cardiovascular Surgical Procedures / methods*
  • Heart Atria / surgery*
  • Humans
  • Postoperative Complications / etiology
  • Transposition of Great Vessels / epidemiology
  • Transposition of Great Vessels / physiopathology
  • Transposition of Great Vessels / surgery*
  • Ventricular Dysfunction, Right