Abstract
We report a novel instance of negative interference during Saccharomyces cerevisiae meiosis, where Cre-mediated recombination between pairs of allelic loxP sites is more frequent than expected. We suggest that endogenous crossover recombination mediates cooperative pairing interactions between all four chromatids of a meiotic bivalent.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Alleles
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Chromatids / genetics*
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Chromosome Pairing
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Chromosomes, Fungal / genetics
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Crossing Over, Genetic
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Meiosis / genetics*
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Models, Genetic
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Recombination, Genetic
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Saccharomyces cerevisiae / cytology*
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Saccharomyces cerevisiae / genetics*
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Sister Chromatid Exchange