AAV-dependent targeting of myostatin function: follistatin strikes back at muscular dystrophy

Gene Ther. 2008 Aug;15(15):1075-6. doi: 10.1038/gt.2008.95. Epub 2008 Jun 5.

Authors

C Colussi, C Gaetano, M C Capogrossi

PMID: 18528431
DOI: 10.1038/gt.2008.95

No abstract available

Publication types

News

MeSH terms

Animals
Dependovirus / genetics
Follistatin / genetics*
Follistatin / metabolism
Genetic Therapy / methods*
Genetic Vectors / administration & dosage
Humans
Mice
Mice, Inbred mdx
Muscular Dystrophy, Duchenne / therapy*
Myostatin
Protein Isoforms / genetics*
Protein Isoforms / metabolism
Transduction, Genetic / methods
Transforming Growth Factor beta / metabolism*

Substances

Follistatin
MSTN protein, human
Mstn protein, mouse
Myostatin
Protein Isoforms
Transforming Growth Factor beta