Cure following gene therapy for recurrent glioblastoma multiforme?

Acta Neurochir (Wien). 2008 Jun;150(6):611-2. doi: 10.1007/s00701-008-1579-9. Epub 2008 May 30.

Abstract

We report a patient with glioblastoma multiforme who is alive and disease-free 13 years following aggressive treatment with multiple surgeries, radiotherapy, chemotherapy, and gene therapy.

Publication types

  • Case Reports

MeSH terms

  • Brain Neoplasms / genetics
  • Brain Neoplasms / therapy*
  • Combined Modality Therapy
  • Disease-Free Survival
  • Follow-Up Studies
  • Gene Transfer Techniques
  • Genetic Therapy*
  • Glioblastoma / genetics
  • Glioblastoma / therapy*
  • Humans
  • Injections, Intralesional
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / genetics
  • Neoplasm Recurrence, Local / therapy*
  • Simplexvirus / genetics
  • Thymidine Kinase / genetics

Substances

  • Thymidine Kinase