Significant differences in nervous and cardiovascular systems state and humoral homeostasis indices were established in relative healthy personnel (62 persons) of Resuscitation Unit and Burn Center in comparison with control group (60 persons). Thalassotherapy has obvious health-improving effect in asthenia clinical symptoms regress, decrease in number of acute respiratory diseases and otorhinolaryngological organs chronic pathology relapses. Sanogenetic effects are realized via normalization of level of cortisol, thyroid-stimulating hormone, immune sate indices and optimization of lipid peroxydation processes.