Metallo-beta-lactamase gene bla(IMP-15) in a class 1 integron, In95, from Pseudomonas aeruginosa clinical isolates from a hospital in Mexico

Antimicrob Agents Chemother. 2008 Aug;52(8):2943-6. doi: 10.1128/AAC.00679-07. Epub 2008 May 19.

Abstract

During 2003, 40 carbapenem-resistant Pseudomonas aeruginosa clinical isolates collected in a Mexican tertiary-care hospital were screened for metallo-beta-lactamase production. Thirteen isolates produced IMP-15, and 12 had a single pulsed-field gel electrophoresis pattern. The bla(IMP-15) gene cassette was inserted in a plasmid-borne integron with a unique array of gene cassettes and was named In95.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Proteins / genetics*
  • Cross Infection / microbiology
  • Electrophoresis, Gel, Pulsed-Field
  • Humans
  • Integrons / genetics*
  • Mexico
  • Models, Genetic
  • Molecular Sequence Data
  • Pseudomonas Infections / microbiology
  • Pseudomonas aeruginosa / enzymology
  • Pseudomonas aeruginosa / genetics*
  • Pseudomonas aeruginosa / isolation & purification
  • beta-Lactamases / genetics*

Substances

  • Bacterial Proteins
  • beta-Lactamases

Associated data

  • GENBANK/EF184216