How Athila retrotransposons survive in the Arabidopsis genome

BMC Genomics. 2008 May 14:9:219. doi: 10.1186/1471-2164-9-219.

Abstract

Background: Transposable elements are selfish genetic sequences which only occasionally provide useful functions to their host species. In addition, models of mobile element evolution assume a second type of selfishness: elements of different families do not cooperate, but they independently fight for their survival in the host genome.

Results: We show that recombination events among distantly related Athila retrotransposons have led to the generation of new Athila lineages. Their pattern of diversification suggests that Athila elements survive in Arabidopsis by a combination of selfish replication and of amplification of highly diverged copies with coding potential. Many Athila elements are non-autonomous but still conserve intact open reading frames which are under the effect of negative, purifying natural selection.

Conclusion: The evolution of these mobile elements is far more complex than hitherto assumed. Strict selfish replication does not explain all the patterns observed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arabidopsis / genetics*
  • DNA, Plant / genetics*
  • Evolution, Molecular
  • Expressed Sequence Tags
  • Genome, Plant*
  • Models, Genetic
  • Phylogeny
  • Recombination, Genetic
  • Retroelements / genetics*

Substances

  • DNA, Plant
  • Retroelements