Midline medulloblastoma versus astrocytoma: the position of the superior medullary velum as a sign for diagnosis

Childs Nerv Syst. 2008 Sep;24(9):1037-41. doi: 10.1007/s00381-008-0635-3. Epub 2008 May 14.

Abstract

Purpose: We wish to describe the position of the superior medullary velum (SMV) in midline posterior fossa tumours as a sign in helping to distinguish between midline medulloblastoma and midline astrocytoma.

Material and methods: Sagittal T1-weighted MRI images of 21 consecutive patients with histologically documented posterior fossa midline astrocytomas (nine cases) and medulloblastomas (12 cases) were reviewed, with respect to the position of the velum medullare superius.

Results: In all medulloblastomas the SMV was superiorly dislocated; in eight astrocytomas it was anteriorly and/or inferiorly disclocated; only in one astrocytoma the SMV presented upward dislocation.

Conclusion: In the differential diagnosis between medulloblastoma and astrocytoma the upward dislocation of the SMV is strongly suggestive of medulloblastoma.

MeSH terms

  • Astrocytoma / pathology*
  • Child
  • Child, Preschool
  • Diagnosis, Differential
  • Female
  • Humans
  • Infant
  • Infratentorial Neoplasms / pathology*
  • Magnetic Resonance Imaging*
  • Male
  • Medulloblastoma / pathology*