Microsurgical anatomy of the diaphragma sellae and its role in directing the pattern of growth of pituitary adenomas

Neurosurgery. 2008 Mar;62(3):717-23; discussion 717-23. doi: 10.1227/01.neu.0000317321.79106.37.

Abstract

Objective: To evaluate the anatomic aspects of the diaphragma sellae and its potential role in directing the growth of a pituitary adenoma.

Methods: Twenty cadaveric heads were dissected and measurements were taken at the level of the diaphragma sellae.

Results: The diaphragma sellae is composed of two layers of dura mater. There is a remarkable variation in the morphology of the diaphragm opening. The average anteroposterior distance of the opening was 7.26 mm (range, 3.4-10.7 mm) and the average lateral-to-lateral distance was 7.33 mm (range, 2.8-14.1 mm).

Conclusion: The variability in the diameter of the opening of the diaphragma sellae could explain the growth of pituitary tumors toward the cavernous sinus or toward the suprasellar region.

MeSH terms

  • Adenoma / pathology*
  • Adenoma / surgery
  • Cadaver
  • Humans
  • Microsurgery
  • Models, Anatomic
  • Neoplasm Invasiveness
  • Pituitary Neoplasms / pathology*
  • Pituitary Neoplasms / surgery
  • Sella Turcica / pathology*
  • Sella Turcica / surgery