Anxiety and salivary cortisol levels in patients with burning mouth syndrome: case-control study

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Apr;105(4):460-5. doi: 10.1016/j.tripleo.2007.10.002.

Abstract

Objective: The objective of this study was to evaluate the anxiety and salivary cortisol levels in patients with burning mouth syndrome.

Study design: A case-control ed into 2 groups: BMS, with diagnosis of the syndrome, and control, without any complaint of burning mouth. Anamnesis, oral examination, sialometry, the application anxiety inventory, and 3 saliva samples for cortisol analysis were done in every patient.

Results: Statistical difference for subjective xerostomia was found on the BMS group (P = .01), but salivary flow rate was normal in both groups. BMS group presented higher anxiety (P = .001) and salivary cortisol levels (P = .003) when compared with the control group.

Conclusion: Higher anxiety and salivary cortisol levels were positively associated with the presence of BMS.

MeSH terms

  • Anxiety / complications*
  • Burning Mouth Syndrome / psychology*
  • Epidemiologic Methods
  • Female
  • Humans
  • Hydrocortisone / analysis*
  • Male
  • Middle Aged
  • Saliva / chemistry*

Substances

  • Hydrocortisone