Mycoplasma meningitis resulting in increased production of cerebrospinal fluid: case report and review of the literature

Childs Nerv Syst. 2008 Jul;24(7):859-62. doi: 10.1007/s00381-008-0590-z. Epub 2008 Feb 28.

Abstract

Purpose: We report a case of increased cerebrospinal fluid (CSF) production in a child with concomitant mycoplasma meningitis.

Materials and methods: This 4-year-old boy presented with a 2-week history of body aches, malaise, and headaches. He developed sudden onset of obtundation, apnea, left eye deviation, and bilateral dilated and unreactive pupils. A ventriculostomy was placed initially for a poor neurologic examination in the setting of likely meningitis. Initial intracranial pressure was high, and CSF production was supraphysiologic for the first few days of empiric, broad-spectrum treatment. Mycoplasma meningitis was diagnosed. The ventriculostomy was weaned after adequate treatment for mycoplasma meningitis.

Results and conclusions: At 4 months follow-up, the child remains shunt-free with only mild cognitive-linguistic impairment. Untreated mycoplasma meningitis may cause raised intracranial pressure (possibly as a result of increased CSF production) and result in a poor neurological examination. In this setting, CSF diversion in the form of an external ventricular drain may be beneficial to preserve neurologic function during treatment with antibiotics.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Cerebrospinal Fluid Pressure / physiology*
  • Child, Preschool
  • Humans
  • Magnetic Resonance Imaging / methods
  • Male
  • Meningitis, Bacterial / complications*
  • Meningitis, Bacterial / pathology
  • Meningitis, Bacterial / surgery
  • Mycoplasma Infections / complications*
  • Mycoplasma Infections / pathology
  • Ventriculostomy / methods