Salivating for knowledge: potential pharmacological agents in tick saliva

PLoS Med. 2008 Feb;5(2):e43. doi: 10.1371/journal.pmed.0050043.

Abstract

Joppe Hovius and colleagues review anticoagulant and immunosuppressive proteins present in tick saliva, and discuss how immunologically targeting such molecules could prevent transmission of tick-borne pathogens.

Publication types

  • Review

MeSH terms

  • Animals
  • Anticoagulants / analysis
  • Anticoagulants / chemistry
  • Humans
  • Immunosuppressive Agents / analysis
  • Immunosuppressive Agents / chemistry
  • Pharmaceutical Preparations* / analysis
  • Pharmaceutical Preparations* / chemistry
  • Saliva / chemistry
  • Saliva / metabolism*
  • Salivation* / physiology
  • Ticks* / chemistry

Substances

  • Anticoagulants
  • Immunosuppressive Agents
  • Pharmaceutical Preparations