Erythema elevatum diutinum with unusual clinical appearance

J Dtsch Dermatol Ges. 2008 Apr;6(4):303-5. doi: 10.1111/j.1610-0387.2008.06589.x. Epub 2008 Feb 11.
[Article in English, German]

Abstract

Erythema elevatum diutinum is a rare chronic inflammatory skin disease of unknown etiology with a histopathology of a leukocytoclastic vasculitis. Clinical findings involve symmetrical livid-erythematous to red-brown papules and plaques or nodules which are initially soft but become firmer. The skin lesions are located over extensor surfaces and often over joints. Early treatment with dapsone, corticosteroids and antibiotics is sometimes effective. A patient with multiple myeloma displayed unusual lesions of erythema elevatum diutinum.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biopsy
  • Diabetes Complications / diagnosis
  • Diabetes Complications / pathology
  • Diagnosis, Differential
  • Disease Progression
  • Elbow*
  • Fingers*
  • Hand Dermatoses / diagnosis*
  • Hand Dermatoses / pathology
  • Hand Dermatoses / surgery
  • Humans
  • Immune Complex Diseases / diagnosis*
  • Immune Complex Diseases / pathology
  • Immune Complex Diseases / surgery
  • Immunoglobulin A / blood
  • Immunoglobulin kappa-Chains / blood
  • Male
  • Microscopy, Electron
  • Multiple Myeloma / diagnosis
  • Multiple Myeloma / pathology
  • Paraproteinemias / diagnosis
  • Paraproteinemias / pathology
  • Skin / pathology
  • Skin Diseases, Papulosquamous / diagnosis*
  • Skin Diseases, Papulosquamous / pathology
  • Skin Diseases, Papulosquamous / surgery
  • Skin Diseases, Vascular / diagnosis*
  • Skin Diseases, Vascular / pathology
  • Skin Diseases, Vascular / surgery
  • Skin Transplantation

Substances

  • Immunoglobulin A
  • Immunoglobulin kappa-Chains