Response of intracranial metastases to epidermal growth factor receptor tyrosine kinase inhibitors: it may all depend on EGFR mutations

J Clin Oncol. 2008 Feb 1;26(4):686. doi: 10.1200/JCO.2007.15.1944.
No abstract available

Publication types

  • Letter
  • Comment

MeSH terms

  • Brain Neoplasms / drug therapy*
  • Brain Neoplasms / secondary*
  • Carcinoma, Non-Small-Cell Lung / drug therapy*
  • Carcinoma, Non-Small-Cell Lung / secondary*
  • ErbB Receptors / antagonists & inhibitors*
  • ErbB Receptors / genetics*
  • Erlotinib Hydrochloride
  • Female
  • Gefitinib
  • Humans
  • Lung Neoplasms / pathology
  • Middle Aged
  • Protein-Tyrosine Kinases / antagonists & inhibitors
  • Quinazolines / therapeutic use
  • Sequence Deletion*

Substances

  • Quinazolines
  • Erlotinib Hydrochloride
  • ErbB Receptors
  • Protein-Tyrosine Kinases
  • Gefitinib