Abstract
A simple assay for tumorigenicity of myoblasts to be transplanted to Duchenne patients has been developed. The assay is based on culture in a soft agar medium for 2-3 weeks. The tumor cell line forms large cell clusters while the normal myoblasts do not proliferate and remain isolated.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Cell Transformation, Neoplastic*
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Cells, Cultured
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Clone Cells
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Culture Techniques / methods
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Humans
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Muscles / cytology*
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Muscles / pathology
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Muscles / transplantation
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Rhabdomyosarcoma / pathology*
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Time Factors
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Tumor Cells, Cultured