[Considerations on the effectiveness of serum-vaccine prophylaxis in maternal-fetal transmission of the hepatitis B virus]

Abstract

Personal experience of sero-vaccino-prophylaxis for the purposes of vertical interruption of hepatitis B transmitted by mother carriers of HBsAG to their children is reported. Special attention is paid to the problem of the failure of such immunitary strategy in high-risk newborns (children of HBsAg, HBeAg and HBV-DNA positive mothers) and some suggestions are made to reduce the risk of this infection.