This report presents the skeletal and dental features of "Myrtis", an 11-year-old female resident of ancient Athens back in 430 BC. Her skeleton was unearthed in an archaeological excavation of a mass burial pit located in the outskirts of Kerameikos' ancient cemetery of Athens. "Myrtis" is believed to have been one of the numerous hapless victims of the Plague of Athens. Her skull was found in relatively intact condition bearing her complete dentition corresponding to the mixed dentition stage. A complete dental and orthodontic diagnosis of Myrtis was conducted based on clinical examination, study of panoramic radiographs, and lateral cephalometric analysis of her skull. No significant dental pathology was reported pertaining to deciduous or permanent teeth of "Myrtis". A Class II skeletal and dental malocclusion was observed. The ectopic labial eruption of the maxillary canines mesially to their retained deciduous predecessors, the ectopic distally directed eruption of a lower first premolar, and a unilaterally missing lower third molar were among the most interesting dental findings reported.