Self-assembled monolayers: solidification of carbamazepine in Form II at an interface

Florence Quist; Jonathan Mooney; Ashok K Kakkar

doi:10.1016/j.colsurfb.2007.09.033

Self-assembled monolayers: solidification of carbamazepine in Form II at an interface

Colloids Surf B Biointerfaces. 2008 Apr 1;62(2):319-23. doi: 10.1016/j.colsurfb.2007.09.033. Epub 2007 Oct 5.

Authors

Florence Quist¹, Jonathan Mooney, Ashok K Kakkar

Affiliation

¹ Department of Chemistry, McGill University, Montreal, Quebec H3A 2K6, Canada.

PMID: 18155451
DOI: 10.1016/j.colsurfb.2007.09.033

Abstract

A self-assembled monolayer incorporating well-spaced biphenyl moieties initiates solidification of carbamazepine at its interface. A detailed analysis of the resulting crystals using X-ray powder diffraction, FTIR-ATR as well as thermomicroscopy, indicates a preference for its crystallization in trigonal (Form II) polymorph.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Biphenyl Compounds / chemistry
Carbamazepine / chemistry*
Chemical Phenomena
Chemistry, Physical
Crystallization
Membranes, Artificial
Microscopy, Atomic Force
Spectroscopy, Fourier Transform Infrared
X-Ray Diffraction

Substances

Biphenyl Compounds
Membranes, Artificial
Carbamazepine