Health care-associated endocarditis caused by Staphylococcus aureus with reduced susceptibility to vancomycin

J Clin Microbiol. 2008 Feb;46(2):810-3. doi: 10.1128/JCM.01004-07. Epub 2007 Dec 12.

Abstract

Infective endocarditis (IE) caused by methicillin-resistant Staphylococcus aureus with reduced vancomycin susceptibility (SARV) has been reported worldwide. We report the successful treatment of a pediatric patient with SARV IE and characterization of the infecting strain. The MIC of vancomycin rose from 1.5 to 2 microg/ml, and the SARV was confirmed by population analysis.

Publication types

  • Case Reports

MeSH terms

  • Acetamides / therapeutic use
  • Anti-Bacterial Agents / therapeutic use
  • Child, Preschool
  • Cross Infection / drug therapy
  • Cross Infection / microbiology*
  • Endocarditis, Bacterial / drug therapy
  • Endocarditis, Bacterial / microbiology*
  • Female
  • Fusidic Acid / therapeutic use
  • Humans
  • Linezolid
  • Methicillin Resistance
  • Microbial Sensitivity Tests
  • Oxazolidinones / therapeutic use
  • Staphylococcal Infections / drug therapy
  • Staphylococcal Infections / microbiology*
  • Staphylococcus aureus / drug effects*
  • Staphylococcus aureus / isolation & purification
  • Vancomycin Resistance*

Substances

  • Acetamides
  • Anti-Bacterial Agents
  • Oxazolidinones
  • Fusidic Acid
  • Linezolid