[Separation of epimers of anisodamine (654-2) with HPLC using chiral additives in the mobile phase]

Yao Xue Xue Bao. 1991;26(7):527-30.
[Article in Chinese]

Abstract

The separation of epimers of anisodamine were studied with HPLC using a reversed phase ODS C18 column. Several chiral additives were tried in the mobile phases. d-Camphorsulfonic acid and L-(+)-dibutyl tartrate showed good resolution ability for the separation of the isomers, a pair of epimers of anisodamine were well separated; while beta-cyclodextrin appeared to have no selectivity for the epimers.

Publication types

  • English Abstract

MeSH terms

  • Chromatography, High Pressure Liquid / methods
  • Solanaceous Alkaloids / chemistry
  • Solanaceous Alkaloids / isolation & purification*
  • Stereoisomerism

Substances

  • Solanaceous Alkaloids
  • anisodamine