First comparative analysis for some hemocoagulation reactions, immune state of acute myocardial infarction has been done in two groups of patients - with mycoplasma infections and without one. Postinfarction complications in the groups were observed. Atherosclerotic plaques of the patients were also studied on a presence of mycoplasmas and a content of strontium and zinc. A tendency to a mild pattern of acute myocardial infarction was observed in patients with mycoplasma infections. The role of mycoplasmas in atherogenesis and acute myocardial infarction is discussed.