Acute myocardial infarction caused by spontaneous postpartum coronary artery dissection

Nat Clin Pract Cardiovasc Med. 2007 Dec;4(12):688-92. doi: 10.1038/ncpcardio1055.

Abstract

Background: A 34-year-old postpartum woman presented at hospital with chest pain. She had experienced an uneventful delivery of a healthy infant and had no known coronary risk factors. Electrocardiography demonstrated an acute myocardial infarction, which resolved on intravenous glyceryl trinitrate infusion. Coronary angiography revealed diffuse narrowing of the left anterior descending artery and tapering of the left main trunk, but there were no obvious hallmarks of intimal dissection.

Investigations: Electrocardiography, coronary angiography, multidetector CT and intravascular ultrasonography.

Diagnosis: Postpartum coronary artery dissection.

Management: The lesion was stabilized with orally administered amlodipine, aspirin, ticlopidine and pitavastatin, along with intravenous heparin and glyceryl trinitrate. The patient was later discharged on bisoprolol, aspirin, pitavastatin and temocapril.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anatomy, Cross-Sectional
  • Aortic Dissection / complications
  • Aortic Dissection / diagnosis*
  • Coronary Aneurysm / complications
  • Coronary Aneurysm / diagnosis*
  • Coronary Angiography
  • Coronary Artery Disease / complications*
  • Coronary Artery Disease / diagnosis*
  • Electrocardiography
  • Female
  • Humans
  • Myocardial Infarction / diagnosis*
  • Myocardial Infarction / etiology*
  • Postpartum Period
  • Rupture, Spontaneous / diagnosis
  • Tomography, X-Ray Computed
  • Ultrasonography, Interventional