Chromate oxidation of alpha-nitro alcohols to alpha-nitro ketones: significant improvements to a classic method

Molecules. 2005 Dec 31;10(12):1458-61. doi: 10.3390/10121458.

Abstract

A series of eight alkyl and aryl alpha-nitro ketones were prepared by the potassium dichromate oxidation of the corresponding nitro alcohols. Short reaction times allowed for the easy isolation of pure nitro ketones that are devoid of starting materials and/or other oxidation side products.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Alcohols / chemistry*
  • Chromates / chemistry*
  • Ketones / chemistry*
  • Molecular Structure
  • Nitro Compounds / chemical synthesis*
  • Nitro Compounds / chemistry*
  • Oxidation-Reduction

Substances

  • Alcohols
  • Chromates
  • Ketones
  • Nitro Compounds