Abstract
Alkylidene indane and ring-expanded scaffolds have been prepared using an enantioselective crotylation/Heck cyclization sequence. Further diversification using consecutive cyclopropanation-Cope rearrangement affords novel chemotypes including spiroindane frameworks.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Alkylation
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Azo Compounds / chemical synthesis
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Azo Compounds / chemistry
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Cyclization
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Indans / chemical synthesis
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Indans / chemistry*
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Indans / classification*
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Magnetic Resonance Spectroscopy
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Models, Molecular
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Molecular Structure
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Spiro Compounds / chemical synthesis
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Spiro Compounds / chemistry
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Stereoisomerism
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Vinyl Compounds / chemical synthesis
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Vinyl Compounds / chemistry
Substances
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Azo Compounds
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Indans
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Spiro Compounds
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Vinyl Compounds
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indan