Ninety-six haploid yeast strains with individual disruptions of open reading frames between YOR097C and YOR192C, constructed for the Saccharomyces genome deletion project, have an additional mutation in the mismatch repair gene MSH3

Genetics. 2007 Nov;177(3):1951-3. doi: 10.1534/genetics.107.079368. Epub 2007 Oct 18.

Abstract

As part of the Saccharomyces Genome Deletion Project, sets of presumably isogenic haploid and diploid strains that differed only by single gene deletions were constructed. We found that one set of 96 strains (containing deletions of ORFs located between YOR097C and YOR192C) in the collection, which was derived from the haploid BY4741, has an additional mutation in the MSH3 mismatch repair gene.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • DNA Mismatch Repair
  • DNA-Binding Proteins / genetics*
  • Fungal Proteins / genetics*
  • Gene Deletion
  • Genes, Fungal*
  • Genome, Fungal
  • Haploidy
  • Microsatellite Repeats
  • MutS Homolog 3 Protein
  • Mutation
  • Open Reading Frames
  • Saccharomyces / genetics*
  • Saccharomyces cerevisiae Proteins

Substances

  • DNA-Binding Proteins
  • Fungal Proteins
  • MSH3 protein, S cerevisiae
  • MutS Homolog 3 Protein
  • Saccharomyces cerevisiae Proteins