Abstract
Topiramate is known to cause ocular side effects such as refractive changes and angle closure. We describe a patient with an electronegative electroretinogram (ERG) which may have been related to topiramate use. Electronegative ERG's have been associated with other drugs in humans as well as topiramate use in rabbits. However, this would be the first suggestion of causality in humans.
Publication types
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Case Reports
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Anticonvulsants / adverse effects*
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Electroretinography / drug effects*
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Female
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Fructose / adverse effects
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Fructose / analogs & derivatives*
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Humans
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Macular Degeneration / chemically induced*
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Macular Degeneration / diagnosis
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Myoclonic Epilepsy, Juvenile / drug therapy
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Retina / drug effects*
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Retina / pathology
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Topiramate
Substances
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Anticonvulsants
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Topiramate
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Fructose