Potent inhibitors of tRNA-guanine transglycosylase, an enzyme linked to the pathogenicity of the Shigella bacterium: charge-assisted hydrogen bonding

Angew Chem Int Ed Engl. 2007;46(43):8266-9. doi: 10.1002/anie.200702961.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Binding Sites
  • Catalysis
  • Crystallography, X-Ray
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / pharmacology*
  • Hydrogen Bonding
  • Pentosyltransferases / antagonists & inhibitors*
  • Pentosyltransferases / chemistry
  • Shigella / enzymology
  • Shigella / pathogenicity*

Substances

  • Enzyme Inhibitors
  • Pentosyltransferases
  • queuine tRNA-ribosyltransferase