Concentration and time dependent growth inhibition and metabolism in vitro by 2',2'-difluoro-deoxycytidine (gemcitabine)

Adv Exp Med Biol. 1991:309A:57-60. doi: 10.1007/978-1-4899-2638-8_12.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antimetabolites, Antineoplastic / pharmacology*
  • Biotransformation
  • Carcinoma, Squamous Cell
  • Cell Division / drug effects*
  • Cell Line
  • Colonic Neoplasms
  • Deoxycytidine / analogs & derivatives*
  • Deoxycytidine / metabolism
  • Deoxycytidine / pharmacology
  • Drug Screening Assays, Antitumor
  • Female
  • Gemcitabine
  • Head and Neck Neoplasms
  • Humans
  • Kinetics
  • Mice
  • Ovarian Neoplasms

Substances

  • Antimetabolites, Antineoplastic
  • Deoxycytidine
  • Gemcitabine