A case of meningoencephalitis associated with G1P[8] rotavirus infection in a Japanese child

Tamako Goto; Hirokazu Kimura; Kei Numazaki; Miho Akiyama; Masahiko Kato; Masahiro Noda; Yasuyuki Nozaki; Keiko Tanaka-Taya; Kiyosu Taniguchi; Takanori Yamagata; Osamu Nishio; Teruko Oogane; Mariko Y Momoi; Nobuhiko Okabe

doi:10.1080/00365540701466249

A case of meningoencephalitis associated with G1P[8] rotavirus infection in a Japanese child

Scand J Infect Dis. 2007;39(11-12):1067-70. doi: 10.1080/00365540701466249. Epub 2007 Jun 28.

Authors

Tamako Goto¹, Hirokazu Kimura, Kei Numazaki, Miho Akiyama, Masahiko Kato, Masahiro Noda, Yasuyuki Nozaki, Keiko Tanaka-Taya, Kiyosu Taniguchi, Takanori Yamagata, Osamu Nishio, Teruko Oogane, Mariko Y Momoi, Nobuhiko Okabe

Affiliation

¹ Department of Pediatrics, Jichi Medical School, Yakushiji, Shimotsuke, Japan.

PMID: 17852929
DOI: 10.1080/00365540701466249

Abstract

We report the case of a 2-y, 11-month-old boy with G1P[8] rotavirus infection accompanied by acute meningoencephalitis. Substitutions in both the VP4 and VP7 genes were found in the identified strain. A commonly circulating G1P[8] rotavirus with such mutations might be associated with the pathogenesis of CNS complications, including meningoencephalitis.

Publication types

Case Reports

MeSH terms

Acyclovir / therapeutic use
Anti-Bacterial Agents / therapeutic use
Antigens, Viral / genetics
Antiviral Agents / therapeutic use
Asian People
Capsid Proteins / genetics
Carbenicillin / therapeutic use
Child, Preschool
Glycerol / therapeutic use
Humans
Japan / ethnology
Male
Meningitis, Viral / diagnosis
Meningitis, Viral / virology*
Phylogeny
Rotavirus / classification*
Rotavirus / genetics*
Rotavirus Infections / virology*

Substances

Anti-Bacterial Agents
Antigens, Viral
Antiviral Agents
Capsid Proteins
VP4 protein, Rotavirus
VP7 protein, Rotavirus
Carbenicillin
Glycerol
Acyclovir