[The use of the lectin test for detecting antineuraminidase antibodies in the sera of vaccinated subjects]

Vopr Virusol. 1991 Nov-Dec;36(6):469-71.
[Article in Russian]

Abstract

The lectin test (a microvariant) was used to study the immunogenicity of live attenuated and inactivated virion divaccines of influenza A (H1N1 + H3N2) and influenza B vaccines in children 3 to 15 years of age. A good correlation was found between the general level of seroconversion of antineuraminidase and antihemagglutinin antibodies in the sera examined. This method is simple and may be useful for titration of large numbers of sera in studies on the immunogenicity of influenza vaccines or peculiarities of anti-influenza humoral immunity.

Publication types

  • Clinical Trial
  • Comparative Study
  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Agglutination Tests / methods
  • Antibodies, Viral / blood*
  • Child
  • Double-Blind Method
  • Humans
  • Influenza A virus / immunology*
  • Influenza B virus / immunology*
  • Influenza Vaccines / immunology*
  • Lectins*
  • Neuraminidase / immunology*
  • Vaccines, Inactivated / immunology

Substances

  • Antibodies, Viral
  • Influenza Vaccines
  • Lectins
  • Vaccines, Inactivated
  • Neuraminidase