Haemarthrosis in patients with mild coagulation factor deficiency

Blood Coagul Fibrinolysis. 1991 Oct;2(5):669-71. doi: 10.1097/00001721-199110000-00014.

Abstract

While haemarthrosis is a common finding in severe factor VIII or IX deficiency, it is unusual in mild coagulation factor deficiencies. We describe three patients with mild factor IX, X or XI deficiency who presented with spontaneous haemarthrosis. All underwent joint puncture with subsequent worsening of the haemarthrosis in the affected joint. This report indicates that: (i) even mild coagulation factor deficiency may be associated with haemarthrosis; (ii) patients with suspected haemarthrosis should undergo routine screening coagulation tests before joint puncture; and (iii) any abnormalities in the screening tests indicate a need for further evaluation of the coagulation status. In such cases puncture of the joint should be deferred and specific therapy started immediately.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Factor X Deficiency / complications*
  • Factor XI Deficiency / complications*
  • Female
  • Hemarthrosis / blood
  • Hemarthrosis / etiology*
  • Hemophilia B / complications*
  • Humans
  • Male
  • Severity of Illness Index