Recognition of pseudolesions of the liver at imaging is important because of their close resemblance to primary liver cancer or metastases. There are several types of pseudolesions: pseudolesions, with mostly straight borders, corresponding to perfusion abnormalities, fatty liver, confluent fibrosis and radiation hepatitis; morphologic changes of the liver; true pseudotumors. The use of multidetector CT and MR imaging increases the likelihood of detecting such lesions in routine practice. Radiologists must recognize these lesions and understand the underlying etiology.