Interferon type I and II antagonism: a novel regulatory mechanism of indoleamine dioxygenase induction in human peripheral blood monocytes and peritoneal macrophages

Adv Exp Med Biol. 1991:294:547-53. doi: 10.1007/978-1-4684-5952-4_64.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
  • Enzyme Induction / drug effects
  • Humans
  • Interferon alpha-2
  • Interferon-alpha / pharmacology*
  • Interferon-beta / pharmacology*
  • Interferon-gamma / pharmacology*
  • Isoquinolines / pharmacology
  • Leukocytes, Mononuclear / enzymology*
  • Macrophages / enzymology*
  • Piperazines / pharmacology
  • Protein Kinase C / antagonists & inhibitors
  • Recombinant Proteins / pharmacology
  • Tetradecanoylphorbol Acetate / pharmacology
  • Tryptophan Oxygenase / biosynthesis*

Substances

  • Interferon alpha-2
  • Interferon-alpha
  • Isoquinolines
  • Piperazines
  • Recombinant Proteins
  • Interferon-beta
  • Interferon-gamma
  • 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
  • Tryptophan Oxygenase
  • Protein Kinase C
  • Tetradecanoylphorbol Acetate