Abstract
The product label of ribavirin states that it is contraindicated during pregnancy, so the risk in its administering during pregnancy is concerned. We show a case of an infant of 22 months of age with no anomalies born from an HCV- and HIV-infected mother under treatment with pegylated interferon, ribavirin and antiretroviral therapy during the first 16 weeks of pregnancy. The infant is neither HIV- nor HCV-infected.
MeSH terms
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Adult
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Anti-Retroviral Agents / therapeutic use*
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Antiretroviral Therapy, Highly Active
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Drug Therapy, Combination
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Female
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HIV Infections / drug therapy*
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Hepatitis C / drug therapy*
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Humans
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Indinavir / therapeutic use
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Infant
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Interferon alpha-2
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Interferon-alpha / therapeutic use*
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Lamivudine / therapeutic use
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Polyethylene Glycols / therapeutic use*
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Pregnancy
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Pregnancy Complications, Infectious / drug therapy*
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Pregnancy Outcome*
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Pregnancy Trimester, First
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Pregnancy Trimester, Second
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Recombinant Proteins
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Ribavirin / adverse effects
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Ribavirin / therapeutic use*
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Treatment Outcome
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Zidovudine / therapeutic use
Substances
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Anti-Retroviral Agents
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Interferon alpha-2
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Interferon-alpha
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Recombinant Proteins
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Lamivudine
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Polyethylene Glycols
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Ribavirin
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Zidovudine
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Indinavir
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peginterferon alfa-2a