Infant of 22 months of age with no anomalies born from a HCV- and HIV-infected mother under treatment with pegylated interferon, ribavirin and antiretroviral therapy during the first 16 weeks of pregnancy

Reprod Toxicol. 2007 Nov-Dec;24(3-4):414-6. doi: 10.1016/j.reprotox.2007.07.002. Epub 2007 Jul 7.

Abstract

The product label of ribavirin states that it is contraindicated during pregnancy, so the risk in its administering during pregnancy is concerned. We show a case of an infant of 22 months of age with no anomalies born from an HCV- and HIV-infected mother under treatment with pegylated interferon, ribavirin and antiretroviral therapy during the first 16 weeks of pregnancy. The infant is neither HIV- nor HCV-infected.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Retroviral Agents / therapeutic use*
  • Antiretroviral Therapy, Highly Active
  • Drug Therapy, Combination
  • Female
  • HIV Infections / drug therapy*
  • Hepatitis C / drug therapy*
  • Humans
  • Indinavir / therapeutic use
  • Infant
  • Interferon alpha-2
  • Interferon-alpha / therapeutic use*
  • Lamivudine / therapeutic use
  • Polyethylene Glycols / therapeutic use*
  • Pregnancy
  • Pregnancy Complications, Infectious / drug therapy*
  • Pregnancy Outcome*
  • Pregnancy Trimester, First
  • Pregnancy Trimester, Second
  • Recombinant Proteins
  • Ribavirin / adverse effects
  • Ribavirin / therapeutic use*
  • Treatment Outcome
  • Zidovudine / therapeutic use

Substances

  • Anti-Retroviral Agents
  • Interferon alpha-2
  • Interferon-alpha
  • Recombinant Proteins
  • Lamivudine
  • Polyethylene Glycols
  • Ribavirin
  • Zidovudine
  • Indinavir
  • peginterferon alfa-2a