Abstract
In continuation of our earlier work on benzothiadiazines, we have prepared a series of nitrofuran, nitrothiophene and arylfuran coupled benzothiadiazines and evaluated them for antimycobacterial and antibacterial activities. One of the compounds 2f has shown good in vitro antimycobacterial activity. All the synthesized compounds have shown moderate to good antibacterial activity.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / chemical synthesis
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Anti-Bacterial Agents / pharmacology
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Antitubercular Agents / chemical synthesis*
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Antitubercular Agents / pharmacology*
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Bacteria / drug effects
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Benzothiadiazines / chemical synthesis*
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Benzothiadiazines / pharmacology*
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Indicators and Reagents
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Microbial Sensitivity Tests
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Mycobacterium tuberculosis / drug effects
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Structure-Activity Relationship
Substances
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Anti-Bacterial Agents
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Antitubercular Agents
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Benzothiadiazines
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Indicators and Reagents