Crystal structure of a biosynthetic sulfo-hirudin complexed to thrombin

J Am Chem Soc. 2007 Sep 5;129(35):10648-9. doi: 10.1021/ja0735002. Epub 2007 Aug 9.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Crystallography, X-Ray
  • Hirudins / chemistry*
  • Models, Molecular
  • Protein Conformation
  • Thrombin / antagonists & inhibitors
  • Thrombin / chemistry*
  • Tyrosine / analogs & derivatives*
  • Tyrosine / chemistry

Substances

  • Hirudins
  • tyrosine O-sulfate
  • Tyrosine
  • Thrombin