Abstract
Temporal lobe epilepsy patients (n = 48) and healthy controls (n = 69) underwent structured psychiatric interview at baseline and 4 years later to characterize the course of DSM-IV Axis I disorders. Adjusting for the influence of prior psychiatric history, epilepsy subjects exhibit significantly greater risk of interval episodes of Total Axis I Disorders and Mood Disorders, indicating a poorer prognosis for these comorbidities in the context of chronic temporal lobe epilepsy.
Publication types
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Comparative Study
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Research Support, N.I.H., Extramural
MeSH terms
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Adolescent
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Adult
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Chronic Disease
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Comorbidity
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Control Groups
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Depressive Disorder, Major / diagnosis
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Depressive Disorder, Major / epidemiology
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Diagnostic and Statistical Manual of Mental Disorders
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Epilepsy, Temporal Lobe / diagnosis
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Epilepsy, Temporal Lobe / epidemiology*
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Female
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Follow-Up Studies
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Humans
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Longitudinal Studies
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Male
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Mental Disorders / diagnosis
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Mental Disorders / epidemiology*
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Middle Aged
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Mood Disorders / diagnosis
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Mood Disorders / epidemiology
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Odds Ratio
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Prognosis
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Prospective Studies
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Psychiatric Status Rating Scales
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Risk Factors